| 10. Jornada | 03.09.2021 | Rosario Central II | - | Boca Juniors II | 1:3 | ||||
| 15. Jornada | 08.10.2021 | Estudiantes II | - | Rosario Central II | 1:1 | ||||
| 16. Jornada | 13.10.2021 | Rosario Central II | - | Patronato de Paraná II | 2:1 | ||||
| 19. Jornada | 29.10.2021 | Unión de Santa Fe II | - | Rosario Central II | 0:0 | ||||
| 20. Jornada | 05.11.2021 | Defensa y Justicia II | - | Rosario Central II | 1:2 | ||||
| 21. Jornada | 20.11.2021 | Rosario Central II | - | Atlético Tucumán II | 4:1 | ||||
| 23. Jornada | 28.11.2021 | Rosario Central II | - | River Plate II | 2:0 | ||||
| 24. Jornada | 03.12.2021 | Lanús II | - | Rosario Central II | 2:3 | ||||
| 25. Jornada | 10.12.2021 | Rosario Central II | - | Huracán II | 2:0 |
Argentina