| 1. Jornada | 06.02.2022 | Blooming | - | Bolívar | 0:7 |  |
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| 2. Jornada | 12.02.2022 | Jorge Wilstermann | - | Blooming | 0:1 | ||||
| 4. Jornada | 26.02.2022 | Blooming | - | Universitario de Vinto | 5:0 | |
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| 5. Jornada | 06.03.2022 | Independiente Petrolero | - | Blooming | 2:3 | |
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| 8. Jornada | 10.04.2022 | Real Tomayapo | - | Blooming | 1:2 | |
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| 10. Jornada | 20.04.2022 | Blooming | - | Jorge Wilstermann | 3:3 |  |
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| 14. Jornada | 13.05.2022 | Blooming | - | Independiente Petrolero | 4:0 | ||||
| 15. Jornada | 15.05.2022 | Always Ready | - | Blooming | 3:0 | |
Bolivia