| 3. Jornada | 30.01.2022 | CD Zap | - | Cafetaleros de Chiapas | 1:4 | ||||
| 4. Jornada | 04.02.2022 | Inter Playa | - | CD Zap | 3:2 | ||||
| 5. Jornada | 12.02.2022 | Inter de Querétaro | - | CD Zap | 0:3 | ||||
| 6. Jornada | 20.02.2022 | CD Zap | - | Montañeses FC | 0:1 | ||||
| 7. Jornada | 26.02.2022 | Leviatán FC | - | CD Zap | 0:4 |  |
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| 9. Jornada | 13.03.2022 | Yalmakan FC | - | CD Zap | 1:1 | ||||
| 10. Jornada | 18.03.2022 | CD Zap | - | Lobos ULMX | 3:1 | ||||
| 13. Jornada | 09.04.2022 | Cañoneros FC | - | CD Zap | 3:2 | |
México