| 2. Jornada | 25.01.2020 | San Lorenzo | - | 12 de Octubre de Itauguá | 1:0 | ||||
| 3. Jornada | 02.02.2020 | Club Olimpia | - | San Lorenzo | 4:2 | ||||
| 4. Jornada | 08.02.2020 | San Lorenzo | - | Club Nacional | 1:1 | ||||
| 5. Jornada | 17.02.2020 | River Plate | - | San Lorenzo | 4:2 |  |
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| 6. Jornada | 25.02.2020 | San Lorenzo | - | Sportivo Luqueño | 0:0 | ||||
| 7. Jornada | 02.03.2020 | Sol de América | - | San Lorenzo | 2:1 | ||||
| 8. Jornada | 08.03.2020 | San Lorenzo | - | Guaireña FC | 1:1 | ||||
| 9. Jornada | 22.07.2020 | General Díaz | - | San Lorenzo | 2:1 | ||||
| 10. Jornada | 25.07.2020 | San Lorenzo | - | Libertad | 1:2 | ||||
| 11. Jornada | 02.08.2020 | Cerro Porteño | - | San Lorenzo | 4:1 | ||||
| 13. Jornada | 13.08.2020 | 12 de Octubre de Itauguá | - | San Lorenzo | 1:0 | ||||
| 14. Jornada | 17.08.2020 | San Lorenzo | - | Club Olimpia | 2:2 | ||||
| 15. Jornada | 21.08.2020 | Club Nacional | - | San Lorenzo | 2:0 | ||||
| 16. Jornada | 26.08.2020 | San Lorenzo | - | River Plate | 0:0 | ||||
| 20. Jornada | 19.09.2020 | San Lorenzo | - | General Díaz | 2:1 | ||||
| 21. Jornada | 27.09.2020 | Libertad | - | San Lorenzo | 3:0 | ||||
| 22. Jornada | 03.10.2020 | San Lorenzo | - | Cerro Porteño | 1:1 | |
Uruguay