| Liga MX | 01.03.21 | Santos Laguna | - | FC Juárez | 3:2 | ||||
| Liga MX | 19.04.21 | Santos Laguna | - | Deportivo Toluca | 3:1 |  |
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| Liga MX | 16.08.21 | Santos Laguna | - | Deportivo Guadalajara | 0:0 | ||||
| Liga MX | 11.09.21 | Club Tijuana | - | Santos Laguna | 2:1 |  |
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| Liga MX | 29.11.21 | UANL Tigres | - | Santos Laguna | 1:0 | ||||
| Liga MX | 13.02.22 | Santos Laguna | - | CF América | 2:3 | ||||
| Liga MX | 11.05.22 | Puebla FC | - | CF América | 1:1 |
Colombia