| Cuartos de final | 27.11.2021 | Santos Laguna [Sub 16] | - | CF Pachuca [Sub 16] | 1:5 |  |
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| Semifinales | 04.12.2021 | CF Pachuca [Sub 16] | - | Club León [Sub 16] | 2:0 | |
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| Final | 09.12.2021 | CF Pachuca [Sub 16] | - | Deportivo Guadalajara [Sub 16] | 2:1 | |
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| Final | 11.12.2021 | Deportivo Guadalajara [Sub 16] | - | CF Pachuca [Sub 16] | 1:0 |
México