| 1. Jornada | 22.07.2023 | Mazatlán FC [] | - | Santos Laguna [] | 3:1 | ||||
| 2. Jornada | 29.07.2023 | Santos Laguna [] | - | Club León [] | 3:2 | ||||
| 3. Jornada | 05.08.2023 | Atlético San Luis [] | - | Santos Laguna [] | 0:2 | ||||
| 4. Jornada | 12.08.2023 | Santos Laguna [] | - | Deportivo Guadalajara [] | 1:1 | ||||
| 7. Jornada | 03.09.2023 | Santos Laguna [] | - | Club Tijuana [] | 2:3 | ||||
| 8. Jornada | 09.09.2023 | Atlas Guadalajara [] | - | Santos Laguna [] | 3:1 | ||||
| 9. Jornada | 16.09.2023 | Santos Laguna [] | - | CF Monterrey [] | 4:2 | ||||
| 13. Jornada | 14.10.2023 | Club Tijuana [] | - | Santos Laguna [] | 3:0 | ||||
| 15. Jornada | 28.10.2023 | Santos Laguna [] | - | UANL Tigres [] | 1:0 | ||||
| 16. Jornada | 04.11.2023 | CF Monterrey [] | - | Santos Laguna [] | 4:2 |
México