| 1. Jornada | 03.02.2025 | Leones FC | - | Boca Juniors de Cali | 1:1 |  |
|||
| 2. Jornada | 10.02.2025 | Orsomarso SC | - | Leones FC | 2:3 | ||||
| 3. Jornada | 18.02.2025 | Leones FC | - | Real Cartagena | 1:2 | ||||
| 4. Jornada | 24.02.2025 | Barranquilla FC | - | Leones FC | 2:3 | |
|||
| 5. Jornada | 03.03.2025 | Tigres FC | - | Leones FC | 1:1 | |
|||
| 6. Jornada | 12.03.2025 | Leones FC | - | Internacional de Palmira | 1:2 | |
|||
| 7. Jornada | 17.03.2025 | Real Santander | - | Leones FC | 1:0 | ||||
| 8. Jornada | 25.03.2025 | Leones FC | - | Real Soacha Cundinamarca | 3:1 | |
|||
| 9. Jornada | 28.03.2025 | Jaguares de Córdoba | - | Leones FC | 2:0 |  |
|||
| 10. Jornada | 06.04.2025 | Leones FC | - | Deportes Quindío | 4:1 | |
|
||
| 11. Jornada | 12.04.2025 | Patriotas FC | - | Leones FC | 3:1 |
Colombia