| 4. Jornada | 09.08.2021 | Alianza Petrolera | - | Deportivo Pasto | 2:0 | ||||
| 5. Jornada | 14.08.2021 | Envigado FC | - | Alianza Petrolera | 2:1 | ||||
| 6. Jornada | 23.08.2021 | Alianza Petrolera | - | Deportivo Cali | 2:3 | ||||
| 9. Jornada | 12.09.2021 | Santa Fe | - | Alianza Petrolera | 1:1 | ||||
| 19. Jornada | 15.11.2021 | Millonarios | - | Alianza Petrolera | 1:1 | ||||
| 20. Jornada | 21.11.2021 | Alianza Petrolera | - | Atlético Junior | 1:1 |
Colombia