| 5. Jornada | 05.03.2022 | The Strongest | - | Nacional Potosí | 1:1 | ||||
| 6. Jornada | 13.03.2022 | Nacional Potosí | - | Real Tomayapo | 5:0 |  |
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| 7. Jornada | 02.04.2022 | Nacional Potosí | - | Club Aurora | 2:1 | ||||
| 12. Jornada | 29.04.2022 | CD Guabirá | - | Nacional Potosí | 1:2 | ||||
| 15. Jornada | 15.05.2022 | Club Aurora | - | Nacional Potosí | 2:3 |  |
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| 16. Jornada | 21.05.2022 | Nacional Potosí | - | Oriente Petrolero | 4:2 |
Bolivia