| 1. Jornada | 11.03.2012 | Colorado Rapids | - | Columbus Crew | 2:0 | ||||
| 1. Jornada | 24.03.2012 | Columbus Crew | - | Impact de Montréal | 2:0 |  |
|||
| 1. Jornada | 31.03.2012 | Toronto FC | - | Columbus Crew | 0:1 | ||||
| 2. Jornada | 07.04.2012 | Columbus Crew | - | New York RB | 1:4 | ||||
| 2. Jornada | 14.04.2012 | Philadelphia Union | - | Columbus Crew | 1:0 | ||||
| 2. Jornada | 29.04.2012 | Columbus Crew | - | Vancouver Whitecaps | 0:1 |
Estados Unidos