| 1. Jornada | 25.07.2021 | Grasshopper Club Zürich | - | Basilea | 0:2 | ||||
| 2. Jornada | 31.07.2021 | BSC Young Boys | - | Grasshopper Club Zürich | 0:0 | ||||
| 3. Jornada | 07.08.2021 | Grasshopper Club Zürich | - | FC Lausanne-Sport | 3:1 |  |
|||
| 4. Jornada | 21.08.2021 | FC Zürich | - | Grasshopper Club Zürich | 2:1 |  |
|||
| 5. Jornada | 29.08.2021 | Grasshopper Club Zürich | - | Servette FC | 1:1 | |
|||
| 7. Jornada | 23.09.2021 | FC Lugano | - | Grasshopper Club Zürich | 1:1 | ||||
| 8. Jornada | 26.09.2021 | Grasshopper Club Zürich | - | FC Sion | 3:1 | ||||
| 9. Jornada | 02.10.2021 | Grasshopper Club Zürich | - | FC St. Gallen | 5:2 | ||||
| 10. Jornada | 17.10.2021 | FC Lausanne-Sport | - | Grasshopper Club Zürich | 3:1 | ||||
| 11. Jornada | 23.10.2021 | Grasshopper Club Zürich | - | FC Zürich | 3:3 | ||||
| 14. Jornada | 21.11.2021 | Servette FC | - | Grasshopper Club Zürich | 3:2 | ||||
| 15. Jornada | 27.11.2021 | Grasshopper Club Zürich | - | FC Lugano | 0:1 | ||||
| 16. Jornada | 05.12.2021 | FC St. Gallen | - | Grasshopper Club Zürich | 0:4 | ||||
| 17. Jornada | 12.12.2021 | Grasshopper Club Zürich | - | FC Luzern | 1:1 |
Ecuador
Estados Unidos 