| 2. Jornada | 07.08.2022 | 1. FC Slovácko | - | FC Hradec Králové | 1:0 | ||||
| 3. Jornada | 14.08.2022 | Dynamo České Budějovice | - | 1. FC Slovácko | 2:2 | ||||
| 4. Jornada | 21.08.2022 | Sigma Olomouc | - | 1. FC Slovácko | 1:2 |  |
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| 5. Jornada | 28.08.2022 | 1. FC Slovácko | - | Slovan Liberec | 1:2 | ||||
| 6. Jornada | 31.08.2022 | Viktoria Plzeň | - | 1. FC Slovácko | 3:0 | ||||
| 9. Jornada | 18.09.2022 | 1. FC Slovácko | - | FK Jablonec | 0:2 | ||||
| 10. Jornada | 02.10.2022 | FC Trinity Zlín | - | 1. FC Slovácko | 0:2 | ||||
| 11. Jornada | 09.10.2022 | 1. FC Slovácko | - | Bohemians Praha 1905 | 2:4 | |
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| 12. Jornada | 16.10.2022 | Baník Ostrava | - | 1. FC Slovácko | 3:1 | |
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| 13. Jornada | 23.10.2022 | 1. FC Slovácko | - | FK Teplice | 2:1 | ||||
| 15. Jornada | 06.11.2022 | 1. FC Slovácko | - | FK Pardubice | 1:0 |
República Checa