| 9. Jornada | 31.10.2020 | Guingamp | - | FC Sochaux | 0:0 | ||||
| 11. Jornada | 23.11.2020 | Guingamp | - | AC Ajaccio | 2:2 |  |
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| 14. Jornada | 05.12.2020 | Toulouse | - | Guingamp | 2:2 | ||||
| 15. Jornada | 12.12.2020 | Guingamp | - | Valenciennes FC | 1:1 | ||||
| 16. Jornada | 18.12.2020 | FC Chambly | - | Guingamp | 3:0 |  |
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| 17. Jornada | 22.12.2020 | Paris FC | - | Guingamp | 3:2 | ||||
| 23. Jornada | 02.02.2021 | Grenoble Foot 38 | - | Guingamp | 2:1 | ||||
| 24. Jornada | 05.02.2021 | Guingamp | - | USL Dunkerque | 0:0 | |
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| 28. Jornada | 02.03.2021 | Guingamp | - | Clermont Foot 63 | 0:5 | ||||
| 29. Jornada | 13.03.2021 | AC Ajaccio | - | Guingamp | 0:2 | ||||
| 30. Jornada | 20.03.2021 | Guingamp | - | Rodez AF | 1:1 | ||||
| 31. Jornada | 03.04.2021 | Troyes | - | Guingamp | 1:0 | ||||
| 34. Jornada | 20.04.2021 | Guingamp | - | FC Chambly | 1:0 | ||||
| 35. Jornada | 24.04.2021 | Guingamp | - | Paris FC | 0:0 | ||||
| 36. Jornada | 01.05.2021 | Amiens SC | - | Guingamp | 0:3 | ||||
| 37. Jornada | 08.05.2021 | Guingamp | - | LB Châteauroux | 2:0 | ||||
| 38. Jornada | 15.05.2021 | Chamois Niortais | - | Guingamp | 0:2 |
Francia