| 1. Jornada | 15.08.2021 | Schalke II | - | Colonia | 1:2 |  |
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| 2. Jornada | 20.08.2021 | Colonia | - | SV Lippstadt 08 | 3:1 | ||||
| 3. Jornada | 25.08.2021 | Rot-Weiß Oberhausen | - | Colonia | 1:0 | ||||
| 4. Jornada | 28.08.2021 | Colonia | - | KFC Uerdingen 05 | 8:2 |  |
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| 6. Jornada | 10.09.2021 | Colonia | - | Bonner SC | 3:2 | ||||
| 7. Jornada | 15.09.2021 | Colonia | - | Alemannia Aachen | 1:3 | ||||
| 8. Jornada | 18.09.2021 | Bor. Mönchengladbach II | - | Colonia | 3:1 | ||||
| 9. Jornada | 25.09.2021 | Colonia | - | Sportfreunde Lotte | 4:0 | ||||
| 5. Jornada | 28.09.2021 | SC Wiedenbrück | - | Colonia | 2:0 | ||||
| 10. Jornada | 01.10.2021 | FC Wegberg-Beeck | - | Colonia | 0:1 |
Alemania