| 1. Jornada | 16.07.2021 | Godoy Cruz II | - | Rosario Central II | 1:1 | ||||
| 2. Jornada | 23.07.2021 | Rosario Central II | - | Vélez Sarsfield II | 3:0 | ||||
| 3. Jornada | 27.07.2021 | Gimnasia de La Plata II | - | Rosario Central II | 4:3 |  |
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| 15. Jornada | 08.10.2021 | Estudiantes II | - | Rosario Central II | 1:1 | ||||
| 16. Jornada | 13.10.2021 | Rosario Central II | - | Patronato de Paraná II | 2:1 | ||||
| 17. Jornada | 18.10.2021 | Platense II | - | Rosario Central II | 0:3 |
Argentina