| 1. Jornada | 07.02.2023 | Defensor Sporting | - | Fénix | 1:3 |  |
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| 2. Jornada | 13.02.2023 | Montevideo Wanderers | - | Defensor Sporting | 1:1 | ||||
| 3. Jornada | 19.02.2023 | Defensor Sporting | - | La Luz | 1:0 | ||||
| 4. Jornada | 26.02.2023 | Defensor Sporting | - | Peñarol | 2:2 | ||||
| 5. Jornada | 04.03.2023 | Montevideo City Torque | - | Defensor Sporting | 0:3 | |
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| 6. Jornada | 13.03.2023 | Defensor Sporting | - | Liverpool | 2:2 | ||||
| 12. Jornada | 23.04.2023 | Defensor Sporting | - | Deportivo Maldonado | 1:1 | |
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| 13. Jornada | 30.04.2023 | River Plate | - | Defensor Sporting | 0:4 | |
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| 14. Jornada | 07.05.2023 | Defensor Sporting | - | Nacional | 2:2 | ||||
| 15. Jornada | 14.05.2023 | Danubio | - | Defensor Sporting | 1:1 |
Uruguay