| 1. Jornada | 22.08.2010 | Liverpool | - | Rampla Juniors | 3:1 |  |
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| 2. Jornada | 29.08.2010 | Rampla Juniors | - | River Plate | 0:1 | ||||
| 3. Jornada | 04.09.2010 | Bella Vista | - | Rampla Juniors | 3:2 | ||||
| 4. Jornada | 19.09.2010 | Rampla Juniors | - | CA Cerro | 0:0 | ||||
| 5. Jornada | 26.09.2010 | Montevideo Wanderers | - | Rampla Juniors | 2:0 | ||||
| 6. Jornada | 03.10.2010 | Rampla Juniors | - | Fénix | 2:2 | ||||
| 7. Jornada | 10.10.2010 | El Tanque Sisley | - | Rampla Juniors | 3:2 | |
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| 8. Jornada | 17.10.2010 | Rampla Juniors | - | Central Español | 2:2 | ||||
| 9. Jornada | 24.10.2010 | Defensor Sporting | - | Rampla Juniors | 4:1 |  |
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| 11. Jornada | 06.11.2010 | Peñarol | - | Rampla Juniors | 1:1 | ||||
| 12. Jornada | 13.11.2010 | Rampla Juniors | - | Tacuarembó | 1:0 | ||||
| 13. Jornada | 20.11.2010 | Rampla Juniors | - | Racing | 1:1 | ||||
| 14. Jornada | 28.11.2010 | Danubio | - | Rampla Juniors | 3:3 | ||||
| 15. Jornada | 05.12.2010 | Rampla Juniors | - | Nacional | 1:2 |
Uruguay