| 6. Jornada | 18.02.2016 | Club San José | - | Jorge Wilstermann | 1:3 | ||||
| 7. Jornada | 28.02.2016 | Universitario de Sucre | - | Club San José | 1:2 | ||||
| 8. Jornada | 06.03.2016 | Club San José | - | Real Potosí | 2:3 | ||||
| 9. Jornada | 13.03.2016 | Nacional Potosí | - | Club San José | 1:1 | ||||
| 10. Jornada | 03.04.2016 | Club San José | - | The Strongest | 3:2 | ||||
| 11. Jornada | 10.04.2016 | Bolívar | - | Club San José | 1:2 | ||||
| 13. Jornada | 21.04.2016 | Sport Boys Warnes | - | Club San José | 2:2 |  |
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| 14. Jornada | 24.04.2016 | Club San José | - | Ciclón | 5:2 | |
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| 15. Jornada | 28.04.2016 | Oriente Petrolero | - | Club San José | 1:0 | ||||
| 16. Jornada | 30.04.2016 | Club San José | - | Blooming | 0:0 | ||||
| 17. Jornada | 05.05.2016 | Jorge Wilstermann | - | Club San José | 2:2 | |
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| 18. Jornada | 07.05.2016 | Club San José | - | Universitario de Sucre | 1:1 | ||||
| 19. Jornada | 12.05.2016 | Real Potosí | - | Club San José | 2:1 | |
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| 20. Jornada | 15.05.2016 | The Strongest | - | Club San José | 4:1 | ||||
| 21. Jornada | 22.05.2016 | Club San José | - | Nacional Potosí | 0:0 | ||||
| 22. Jornada | 25.05.2016 | Petrolero de Yacuiba | - | Club San José | 2:0 |
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