| 1. Jornada | 24.01.2021 | Junior Managua | - | Managua FC | 1:3 |  |
|||
| 2. Jornada | 28.01.2021 | ART Municipal Jalapa | - | Junior Managua | 1:1 | ||||
| 3. Jornada | 31.01.2021 | Junior Managua | - | Club Deportivo Ocotal | 0:0 | ||||
| 10. Jornada | 07.03.2021 | Managua FC | - | Junior Managua | 3:1 | ||||
| 11. Jornada | 14.03.2021 | Junior Managua | - | ART Municipal Jalapa | 2:1 | |
|||
| 12. Jornada | 01.04.2021 | Club Deportivo Ocotal | - | Junior Managua | 2:1 | ||||
| 14. Jornada | 18.04.2021 | Chinandega | - | Junior Managua | 2:1 | ||||
| 15. Jornada | 25.04.2021 | Junior Managua | - | Diriangén FC | 0:1 | ||||
| 16. Jornada | 29.04.2021 | Real Madriz | - | Junior Managua | 1:2 | ||||
| 17. Jornada | 02.05.2021 | Junior Managua | - | Real Estelí FC | 0:2 | ||||
| 18. Jornada | 05.05.2021 | Juventus Managua | - | Junior Managua | 2:2 |
Nicaragua