| 4. Jornada | 28.02.2022 | Jorge Wilstermann | - | Independiente Petrolero | 1:0 | ||||
| 5. Jornada | 06.03.2022 | Always Ready | - | Jorge Wilstermann | 0:0 | ||||
| 6. Jornada | 13.03.2022 | Club Aurora | - | Jorge Wilstermann | 1:0 | ||||
| 7. Jornada | 02.04.2022 | Jorge Wilstermann | - | Real Tomayapo | 1:2 | ||||
| 8. Jornada | 09.04.2022 | Bolívar | - | Jorge Wilstermann | 0:1 | ||||
| 10. Jornada | 20.04.2022 | Blooming | - | Jorge Wilstermann | 3:3 | ||||
| 11. Jornada | 23.04.2022 | Jorge Wilstermann | - | Universitario de Vinto | 1:1 | ||||
| 12. Jornada | 01.05.2022 | Independiente Petrolero | - | Jorge Wilstermann | 3:2 | ||||
| 13. Jornada | 08.05.2022 | Jorge Wilstermann | - | Club Aurora | 0:0 | ||||
| 16. Jornada | 22.05.2022 | Jorge Wilstermann | - | Bolívar | 1:4 |  |
Bolivia