| 1. Jornada | 24.07.2011 | Pumas UNAM | - | Club San Luis | 2:0 | ||||
| 2. Jornada | 31.07.2011 | Club San Luis | - | Estudiantes Tecos | 2:1 | ||||
| 5. Jornada | 14.08.2011 | Club San Luis | - | CF Monterrey | 1:0 | ||||
| 6. Jornada | 21.08.2011 | UANL Tigres | - | Club San Luis | 1:0 | ||||
| 7. Jornada | 28.08.2011 | Club San Luis | - | Deportivo Guadalajara | 2:0 |  |
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| 3. Jornada | 04.09.2011 | Club San Luis | - | Monarcas Morelia | 2:3 | ||||
| 8. Jornada | 11.09.2011 | Atlas Guadalajara | - | Club San Luis | 1:1 |  |
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| 4. Jornada | 15.09.2011 | CF América | - | Club San Luis | 2:2 | ||||
| 9. Jornada | 18.09.2011 | Club San Luis | - | Santos Laguna | 0:1 | ||||
| 10. Jornada | 25.09.2011 | CF Pachuca | - | Club San Luis | 1:1 | ||||
| 11. Jornada | 02.10.2011 | Club San Luis | - | Puebla FC | 2:1 | |
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| 12. Jornada | 09.10.2011 | Atlante | - | Club San Luis | 1:1 | ||||
| 13. Jornada | 16.10.2011 | Club San Luis | - | Cruz Azul | 1:1 | ||||
| 14. Jornada | 23.10.2011 | Jaguares Chiapas | - | Club San Luis | 3:1 | |
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| 15. Jornada | 27.10.2011 | Club San Luis | - | Gallos Blancos (old) | 2:1 | ||||
| 16. Jornada | 30.10.2011 | Club Tijuana | - | Club San Luis | 0:0 |
Colombia