| 2. Jornada | 16.04.2010 | Toronto FC | - | Philadelphia Union | 2:1 |  |
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| 2. Jornada | 18.04.2010 | Colorado Rapids | - | Toronto FC | 3:1 | |
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| 2. Jornada | 25.04.2010 | Toronto FC | - | Seattle Sounders | 2:0 | |
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| 3. Jornada | 02.05.2010 | Real Salt Lake | - | Toronto FC | 2:1 | ||||
| 3. Jornada | 08.05.2010 | Toronto FC | - | Chicago Fire | 4:1 | ||||
| 3. Jornada | 16.05.2010 | Los Angeles Galaxy | - | Toronto FC | 0:0 |  |
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| 5. Jornada | 10.07.2010 | Toronto FC | - | Colorado Rapids | 1:0 | ||||
| 5. Jornada | 17.07.2010 | Philadelphia Union | - | Toronto FC | 2:1 | ||||
| 6. Jornada | 12.08.2010 | New York RB | - | Toronto FC | 1:0 | ||||
| 6. Jornada | 29.08.2010 | Toronto FC | - | Real Salt Lake | 0:0 | ||||
| 7. Jornada | 05.09.2010 | FC Dallas | - | Toronto FC | 1:0 | ||||
| 7. Jornada | 09.09.2010 | Chicago Fire | - | Toronto FC | 0:0 | |
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| 7. Jornada | 19.09.2010 | Houston Dynamo | - | Toronto FC | 1:2 | ||||
| 8. Jornada | 10.10.2010 | CD Chivas | - | Toronto FC | 3:0 |
Rusia