| 1. Jornada | 22.01.2020 | Blooming | - | Real Santa Cruz | 1:1 | ||||
| 2. Jornada | 27.01.2020 | Real Santa Cruz | - | The Strongest | 3:2 | ||||
| 4. Jornada | 02.02.2020 | Real Potosí | - | Real Santa Cruz | 2:1 |  |
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| 3. Jornada | 05.02.2020 | Real Santa Cruz | - | Club San José | 1:1 | ||||
| 6. Jornada | 14.02.2020 | Jorge Wilstermann | - | Real Santa Cruz | 0:0 | ||||
| 7. Jornada | 16.02.2020 | Real Santa Cruz | - | Oriente Petrolero | 1:5 | ||||
| 8. Jornada | 22.02.2020 | Atlético Palmaflor | - | Real Santa Cruz | 2:1 |  |
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| 21. Jornada | 19.12.2020 | Real Santa Cruz | - | Atlético Palmaflor | 2:1 | |
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| 23. Jornada | 24.12.2020 | Real Santa Cruz | - | Royal Pari | 2:4 | ||||
| 25. Jornada | 29.12.2020 | Real Santa Cruz | - | CD Guabirá | 4:4 | ||||
| 26. Jornada | 31.12.2020 | Club Aurora | - | Real Santa Cruz | 1:1 |
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