| 1. Jornada | 11.02.2022 | Platense II | - | Talleres de Córdoba II | 1:1 |  |
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| 7. Jornada | 21.03.2022 | Tigre II | - | Platense II | 4:1 | |
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| 5. Jornada | 28.03.2022 | Unión de Santa Fe II | - | Platense II | 0:4 | |
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| 8. Jornada | 04.04.2022 | Newell's Old Boys II | - | Platense II | 1:2 | ||||
| 10. Jornada | 15.04.2022 | San Lorenzo II | - | Platense II | 1:1 |  |
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| 11. Jornada | 20.04.2022 | Platense II | - | Gimnasia de La Plata II | 1:0 | |
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| 12. Jornada | 25.04.2022 | Defensa y Justicia II | - | Platense II | 1:1 | ||||
| 13. Jornada | 02.05.2022 | Platense II | - | Argentinos Juniors II | 1:1 | ||||
| 14. Jornada | 05.05.2022 | River Plate II | - | Platense II | 2:2 | |
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