| 1. Jornada | 19.07.2021 | Central Córdoba SdE II | - | Banfield II | 1:2 | ||||
| 2. Jornada | 23.07.2021 | Banfield II | - | Boca Juniors II | 1:3 | ||||
| 3. Jornada | 27.07.2021 | Unión de Santa Fe II | - | Banfield II | 0:1 | ||||
| 4. Jornada | 30.07.2021 | San Lorenzo II | - | Banfield II | 2:3 | ||||
| 5. Jornada | 06.08.2021 | Banfield II | - | Talleres de Córdoba II | 3:0 | ||||
| 6. Jornada | 13.08.2021 | Argentinos Juniors II | - | Banfield II | 0:0 | ||||
| 8. Jornada | 24.08.2021 | Patronato de Paraná II | - | Banfield II | 1:1 | ||||
| 9. Jornada | 27.08.2021 | Banfield II | - | Platense II | 1:3 | ||||
| 10. Jornada | 06.09.2021 | Racing Club II | - | Banfield II | 1:2 | ||||
| 11. Jornada | 14.09.2021 | Banfield II | - | Rosario Central II | 1:3 | ||||
| 14. Jornada | 01.10.2021 | Colón de Santa Fe II | - | Banfield II | 2:0 | ||||
| 17. Jornada | 18.10.2021 | Banfield II | - | Huracán II | 1:2 | ||||
| 21. Jornada | 16.11.2021 | Banfield II | - | Aldosivi II | 0:1 | ||||
| 23. Jornada | 01.12.2021 | Banfield II | - | Independiente II | 1:1 | ||||
| 24. Jornada | 06.12.2021 | Newell's Old Boys II | - | Banfield II | 2:0 | ||||
| 25. Jornada | 09.12.2021 | Banfield II | - | Arsenal de Sarandí II | 1:1 |
Argentina