| 3. Jornada | 11.08.2021 | Luis Ángel Firpo | - | Platense Zacatecoluca | 3:2 |  |
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| 4. Jornada | 15.08.2021 | Alianza | - | Luis Ángel Firpo | 2:2 | |
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| 5. Jornada | 22.08.2021 | AD Chalatenango | - | Luis Ángel Firpo | 0:2 | ||||
| 6. Jornada | 25.08.2021 | Luis Ángel Firpo | - | Once Municipal | 2:2 | |
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| 7. Jornada | 29.08.2021 | FAS | - | Luis Ángel Firpo | 3:1 | ||||
| 8. Jornada | 12.09.2021 | Luis Ángel Firpo | - | Isidro Metapán | 1:1 |  |
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| 10. Jornada | 19.09.2021 | Luis Ángel Firpo | - | Santa Tecla FC | 0:0 | ||||
| 19. Jornada | 14.11.2021 | Isidro Metapán | - | Luis Ángel Firpo | 2:1 | |
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| 20. Jornada | 18.11.2021 | Luis Ángel Firpo | - | Atlético Marte | 2:0 | ||||
| 22. Jornada | 27.11.2021 | Luis Ángel Firpo | - | CD Águila | 1:0 |
El Salvador