| 1. Jornada | 24.01.2010 | Peñarol | - | Montevideo Wanderers | 4:2 | ||||
| 2. Jornada | 30.01.2010 | Rampla Juniors | - | Montevideo Wanderers | 2:1 | ||||
| 3. Jornada | 06.02.2010 | Fénix | - | Montevideo Wanderers | 2:1 | ||||
| 4. Jornada | 13.02.2010 | Montevideo Wanderers | - | Cerrito | 1:2 |  |
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| 5. Jornada | 21.02.2010 | Atenas | - | Montevideo Wanderers | 0:2 | ||||
| 6. Jornada | 27.02.2010 | Montevideo Wanderers | - | Central Español | 1:1 | ||||
| 7. Jornada | 06.03.2010 | Nacional | - | Montevideo Wanderers | 2:1 | ||||
| 8. Jornada | 13.03.2010 | Montevideo Wanderers | - | Racing | 1:2 | ||||
| 9. Jornada | 21.03.2010 | CA Cerro | - | Montevideo Wanderers | 1:2 | ||||
| 10. Jornada | 28.03.2010 | Montevideo Wanderers | - | Danubio | 1:3 | ||||
| 11. Jornada | 04.04.2010 | Montevideo Wanderers | - | Cerro Largo | 7:1 | ||||
| 12. Jornada | 11.04.2010 | Liverpool | - | Montevideo Wanderers | 1:1 | ||||
| 13. Jornada | 18.04.2010 | Montevideo Wanderers | - | Tacuarembó | 2:1 | |
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| 14. Jornada | 25.04.2010 | Defensor Sporting | - | Montevideo Wanderers | 2:0 | ||||
| 15. Jornada | 02.05.2010 | Montevideo Wanderers | - | River Plate | 2:2 |
Uruguay