| 1. Jornada | 25.08.2010 | Montevideo Wanderers | - | Nacional | 1:1 |  |
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| 3. Jornada | 05.09.2010 | Montevideo Wanderers | - | Tacuarembó | 2:0 | ||||
| 4. Jornada | 19.09.2010 | Defensor Sporting | - | Montevideo Wanderers | 1:2 | ||||
| 2. Jornada | 23.09.2010 | Peñarol | - | Montevideo Wanderers | 2:1 | ||||
| 5. Jornada | 26.09.2010 | Montevideo Wanderers | - | Rampla Juniors | 2:0 | ||||
| 6. Jornada | 02.10.2010 | Racing | - | Montevideo Wanderers | 0:2 | |
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| 7. Jornada | 10.10.2010 | Montevideo Wanderers | - | Danubio | 1:1 | ||||
| 8. Jornada | 17.10.2010 | El Tanque Sisley | - | Montevideo Wanderers | 1:1 | ||||
| 9. Jornada | 23.10.2010 | Montevideo Wanderers | - | Fénix | 2:2 | ||||
| 10. Jornada | 30.10.2010 | Central Español | - | Montevideo Wanderers | 2:1 | ||||
| 11. Jornada | 07.11.2010 | Montevideo Wanderers | - | Bella Vista | 0:2 | ||||
| 12. Jornada | 13.11.2010 | CA Cerro | - | Montevideo Wanderers | 1:1 | ||||
| 14. Jornada | 28.11.2010 | Liverpool | - | Montevideo Wanderers | 0:2 |  |
Uruguay