| 1. Jornada | 24.07.2021 | FK Pardubice | - | MFK Karviná | 2:2 | ||||
| 2. Jornada | 31.07.2021 | MFK Karviná | - | FC Hradec Králové | 1:1 | ||||
| 3. Jornada | 07.08.2021 | Sparta Praga | - | MFK Karviná | 2:0 | ||||
| 5. Jornada | 22.08.2021 | Viktoria Plzeň | - | MFK Karviná | 2:0 |  |
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| 15. Jornada | 21.11.2021 | MFK Karviná | - | Slovan Liberec | 1:2 | ||||
| 12. Jornada | 24.11.2021 | MFK Karviná | - | Baník Ostrava | 1:2 | ||||
| 13. Jornada | 01.12.2021 | Bohemians Praha 1905 | - | MFK Karviná | 3:0 |
República Checa