| 1. Jornada | 10.02.2022 | Vélez Sarsfield II | - | Aldosivi II | 3:2 | ||||
| 2. Jornada | 15.02.2022 | Rosario Central II | - | Vélez Sarsfield II | 1:1 | ||||
| 3. Jornada | 20.02.2022 | Vélez Sarsfield II | - | Independiente II | 0:0 | ||||
| 5. Jornada | 05.03.2022 | Vélez Sarsfield II | - | Estudiantes II | 0:2 | ||||
| 6. Jornada | 13.03.2022 | Arsenal de Sarandí II | - | Vélez Sarsfield II | 1:0 | ||||
| 7. Jornada | 20.03.2022 | Argentinos Juniors II | - | Vélez Sarsfield II | 3:3 | ||||
| 9. Jornada | 08.04.2022 | Vélez Sarsfield II | - | Boca Juniors II | 2:3 |  |
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| 11. Jornada | 19.04.2022 | Vélez Sarsfield II | - | Central Córdoba SdE II | 1:0 |
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