| 11. Jornada | 06.11.2020 | FC Den Bosch | - | Jong PSV | 1:2 | ||||
| 13. Jornada | 20.11.2020 | MVV | - | Jong PSV | 3:3 | ||||
| 12. Jornada | 24.11.2020 | Jong PSV | - | FC Utrecht (J) | 1:1 |  |
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| 14. Jornada | 27.11.2020 | Helmond Sport | - | Jong PSV | 1:0 | ||||
| 10. Jornada | 30.11.2020 | Jong PSV | - | SC Cambuur | 0:1 | ||||
| 16. Jornada | 11.12.2020 | TOP Oss | - | Jong PSV | 3:2 | ||||
| 17. Jornada | 21.12.2020 | Jong PSV | - | Almere City FC | 1:2 | ||||
| 18. Jornada | 05.01.2021 | Jong PSV | - | Go Ahead Eagles | 2:3 | ||||
| 21. Jornada | 22.01.2021 | SC Cambuur | - | Jong PSV | 5:1 | ||||
| 24. Jornada | 23.02.2021 | Jong PSV | - | Helmond Sport | 2:2 | ||||
| 34. Jornada | 19.04.2021 | Jong PSV | - | De Graafschap | 0:2 | ||||
| 36. Jornada | 30.04.2021 | Telstar | - | Jong PSV | 2:2 | ||||
| 35. Jornada | 03.05.2021 | Jong PSV | - | TOP Oss | 0:0 | ||||
| 37. Jornada | 07.05.2021 | Jong PSV | - | FC Volendam | 0:1 | ||||
| 38. Jornada | 12.05.2021 | Almere City FC | - | Jong PSV | 1:1 |
Países Bajos