| 26. Jornada | 04.08.2021 | Liga de Portoviejo | - | Gualaceo SC | 1:1 | ||||
| 27. Jornada | 11.08.2021 | Gualaceo SC | - | El Nacional | 1:0 | ||||
| 28. Jornada | 18.08.2021 | Gualaceo SC | - | Independiente Juniors | 2:0 |  |
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| 29. Jornada | 26.08.2021 | Guayaquil SC | - | Gualaceo SC | 0:2 | ||||
| 30. Jornada | 01.09.2021 | Gualaceo SC | - | Chacaritas FC | 0:1 | |
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| 34. Jornada | 29.09.2021 | Gualaceo SC | - | Liga de Portoviejo | 1:0 | ||||
| 36. Jornada | 13.10.2021 | Gualaceo SC | - | Atlético Santo Domingo | 1:0 |
Argentina