| 1. Jornada | 04.04.2021 | Deportes Iquique | - | Coquimbo Unido | 2:3 | ||||
| 3. Jornada | 25.04.2021 | Deportes Iquique | - | San Marcos | 1:2 | ||||
| 4. Jornada | 03.05.2021 | Barnechea | - | Deportes Iquique | 3:1 | ||||
| 5. Jornada | 09.05.2021 | Deportes Iquique | - | San Luis | 0:0 | ||||
| 6. Jornada | 18.05.2021 | Deportes Copiapó | - | Deportes Iquique | 0:2 | ||||
| 14. Jornada | 07.08.2021 | Deportes Iquique | - | Deportes Temuco | 2:2 | ||||
| 19. Jornada | 05.09.2021 | Deportes Iquique | - | Barnechea | 4:2 | ||||
| 20. Jornada | 16.09.2021 | San Luis | - | Deportes Iquique | 1:1 | ||||
| 21. Jornada | 23.09.2021 | Deportes Iquique | - | Deportes Copiapó | 2:1 | ||||
| 22. Jornada | 27.09.2021 | CD Magallanes | - | Deportes Iquique | 2:2 | ||||
| 23. Jornada | 03.10.2021 | Deportes Iquique | - | Santa Cruz | 6:1 | ||||
| 24. Jornada | 08.10.2021 | Universidad de Concepción | - | Deportes Iquique | 3:1 | ||||
| 30. Jornada | 13.11.2021 | Deportes Iquique | - | Puerto Montt | 4:2 |
Chile