| 1. Jornada | 26.07.2015 | Santos Laguna | - | Club León | 1:3 |  |
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| 2. Jornada | 02.08.2015 | Club León | - | CD Veracruz | 4:1 | |
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| 3. Jornada | 09.08.2015 | Cruz Azul | - | Club León | 2:0 | ||||
| 4. Jornada | 13.08.2015 | Club León | - | UANL Tigres | 2:1 | ||||
| 5. Jornada | 16.08.2015 | Monarcas Morelia | - | Club León | 3:4 | |
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| 6. Jornada | 23.08.2015 | Club León | - | Deportivo Guadalajara | 1:0 | ||||
| 7. Jornada | 30.08.2015 | Deportivo Toluca | - | Club León | 1:3 | ||||
| 8. Jornada | 13.09.2015 | Chiapas FC | - | Club León | 6:2 | |
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| 9. Jornada | 20.09.2015 | Club León | - | Club Tijuana | 2:1 | ||||
| 10. Jornada | 26.09.2015 | Gallos Blancos | - | Club León | 3:0 | ||||
| 11. Jornada | 30.09.2015 | Club León | - | CF América | 3:0 | |
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| 12. Jornada | 04.10.2015 | CF Monterrey | - | Club León | 4:0 | ||||
| 13. Jornada | 18.10.2015 | Club León | - | Pumas UNAM | 1:3 | ||||
| 14. Jornada | 26.10.2015 | Puebla FC | - | Club León | 1:0 | ||||
| 15. Jornada | 01.11.2015 | Club León | - | Atlas Guadalajara | 2:1 | |
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| 16. Jornada | 08.11.2015 | CF Pachuca | - | Club León | 3:2 | |
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| 17. Jornada | 22.11.2015 | Club León | - | Dorados de Sinaloa | 3:0 | |
Argentina
México 
