| 1. Jornada | 06.01.2018 | Atlas Guadalajara | - | Club León | 1:2 |  |
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| 2. Jornada | 14.01.2018 | Club León | - | Deportivo Toluca | 3:1 | ||||
| 3. Jornada | 21.01.2018 | Cruz Azul | - | Club León | 0:0 | ||||
| 4. Jornada | 28.01.2018 | Club León | - | Club Necaxa | 0:4 | ||||
| 5. Jornada | 04.02.2018 | CF Monterrey | - | Club León | 5:1 | ||||
| 6. Jornada | 11.02.2018 | Club León | - | Puebla FC | 2:1 | |
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| 7. Jornada | 15.02.2018 | Santos Laguna | - | Club León | 5:1 | |
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| 8. Jornada | 18.02.2018 | Club León | - | Gallos Blancos | 1:1 | ||||
| 9. Jornada | 25.02.2018 | CF Pachuca | - | Club León | 2:1 | |
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| 10. Jornada | 04.03.2018 | Club León | - | Pumas UNAM | 3:0 | |
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| 13. Jornada | 01.04.2018 | UANL Tigres | - | Club León | 4:1 | |
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| 14. Jornada | 08.04.2018 | Club León | - | Monarcas Morelia | 2:3 | |
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| 15. Jornada | 16.04.2018 | CD Veracruz | - | Club León | 1:2 | |
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| 16. Jornada | 22.04.2018 | Club León | - | Club Tijuana | 1:1 | ||||
| 17. Jornada | 29.04.2018 | Deportivo Guadalajara | - | Club León | 0:2 | |
Argentina
México 
