| 2. Jornada | 15.01.2022 | UANL Tigres [Sub 20] | - | Puebla FC [Sub 20] | 4:1 | ||||
| 4. Jornada | 06.02.2022 | UANL Tigres [Sub 20] | - | Mazatlán FC [Sub 20] | 3:2 | ||||
| 6. Jornada | 19.02.2022 | UANL Tigres [Sub 20] | - | Atlético San Luis [Sub 20] | 1:1 | ||||
| 8. Jornada | 02.03.2022 | UANL Tigres [Sub 20] | - | Cruz Azul [Sub 20] | 1:1 | ||||
| 11. Jornada | 19.03.2022 | UANL Tigres [Sub 20] | - | CF Monterrey [Sub 20] | 0:1 | ||||
| 16. Jornada | 23.04.2022 | UANL Tigres [Sub 20] | - | CF América [Sub 20] | 3:1 |
México