| 16. Jornada | 22.04.2021 | El Entag El Harby | - | Zamalek | 0:2 |  |
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| 21. Jornada | 10.05.2021 | Al Ahly SC | - | Zamalek | 1:1 | ||||
| 22. Jornada | 14.05.2021 | Zamalek | - | ENPPI | 3:1 | |
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| 23. Jornada | 20.05.2021 | Zamalek | - | Tala'ea El Gaish SC | 2:1 | ||||
| 24. Jornada | 24.05.2021 | Zamalek | - | Al Masry Club | 3:2 | ||||
| 26. Jornada | 17.06.2021 | Zamalek | - | Aswan SC | 3:0 | ||||
| 27. Jornada | 28.06.2021 | Misr lel-Maqasah SC | - | Zamalek | 0:1 | ||||
| 28. Jornada | 07.08.2021 | Zamalek | - | Ghazl Al Mehalla | 3:0 | ||||
| 29. Jornada | 10.08.2021 | Ittihad El Iskandary | - | Zamalek | 1:2 |  |
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| 30. Jornada | 14.08.2021 | Ismaily | - | Zamalek | 0:2 | |
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| 32. Jornada | 20.08.2021 | Ceramica Cleopatra | - | Zamalek | 1:2 | ||||
| 33. Jornada | 24.08.2021 | Zamalek | - | El Entag El Harby | 2:0 |
Egipto