| 1. Jornada | 05.09.2021 | Unión Adarve | - | Gimnástica Segoviana | 4:1 | ||||
| 2. Jornada | 11.09.2021 | Coruxo FC | - | Unión Adarve | 1:2 | ||||
| 3. Jornada | 19.09.2021 | CD Cristo Atlético | - | Unión Adarve | 1:1 | ||||
| 4. Jornada | 26.09.2021 | Unión Adarve | - | CDA Navalcarnero | 3:0 | ||||
| 5. Jornada | 03.10.2021 | Real Avilés | - | Unión Adarve | 2:1 | ||||
| 7. Jornada | 16.10.2021 | UP Langreo | - | Unión Adarve | 1:1 | ||||
| 8. Jornada | 24.10.2021 | Unión Adarve | - | Unión Club Ceares | 2:1 | ||||
| 11. Jornada | 14.11.2021 | SD Compostela | - | Unión Adarve | 1:1 |
Guinea-Bissau