| 8. Jornada | 25.09.2010 | Hereford United | - | Southend United | 1:3 | ||||
| 9. Jornada | 28.09.2010 | Gillingham FC | - | Southend United | 0:0 | ||||
| 10. Jornada | 02.10.2010 | Southend United | - | Lincoln City | 1:0 | ||||
| 11. Jornada | 09.10.2010 | Chesterfield FC | - | Southend United | 2:1 | ||||
| 12. Jornada | 16.10.2010 | Southend United | - | Crewe Alexandra | 0:2 | ||||
| 13. Jornada | 23.10.2010 | Bury FC | - | Southend United | 1:0 |
Gales