| 1. Jornada | 23.07.2022 | Sporting San Miguelito | - | Alianza | 0:1 | ||||
| 2. Jornada | 31.07.2022 | Plaza Amador | - | Sporting San Miguelito | 1:1 | ||||
| 3. Jornada | 08.08.2022 | Sporting San Miguelito | - | Árabe Unido | 0:0 | ||||
| 5. Jornada | 14.08.2022 | Potros del Este | - | Sporting San Miguelito | 1:3 |  |
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| 6. Jornada | 21.08.2022 | Sporting San Miguelito | - | UD Universitario | 2:2 | ||||
| 7. Jornada | 28.08.2022 | Herrera FC | - | Sporting San Miguelito | 0:0 | ||||
| 8. Jornada | 03.09.2022 | Sporting San Miguelito | - | Veraguas United | 3:2 | ||||
| 9. Jornada | 12.09.2022 | Sporting San Miguelito | - | San Francisco FC | 2:1 | ||||
| 15. Jornada | 17.10.2022 | Tauro FC | - | Sporting San Miguelito | 2:0 |
Panamá
El Salvador