| 2. Jornada | 01.08.2021 | FK Chayka | - | FK SKA Rostov | 0:1 | ||||
| 3. Jornada | 08.08.2021 | FK SKA Rostov | - | Anzhi Makhachkala | 0:1 | ||||
| 4. Jornada | 15.08.2021 | FK Druzhba | - | FK SKA Rostov | 1:4 | ||||
| 5. Jornada | 21.08.2021 | FK SKA Rostov | - | Alania-2 Vladikavkaz | 5:0 | ||||
| 8. Jornada | 08.09.2021 | FK Dinamo Makhachkala | - | FK SKA Rostov | 0:1 | ||||
| 9. Jornada | 12.09.2021 | FK SKA Rostov | - | Rotor-2 Volgograd | 1:0 | ||||
| 10. Jornada | 20.09.2021 | FK Tuapse | - | FK SKA Rostov | 0:3 | ||||
| 13. Jornada | 10.10.2021 | Chernomorets Novorossisk | - | FK SKA Rostov | 0:1 |  |
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| 14. Jornada | 17.10.2021 | FK SKA Rostov | - | FK Yessentuki | 1:0 | |
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| 19. Jornada | 19.11.2021 | Anzhi Makhachkala | - | FK SKA Rostov | 0:0 | ||||
| 20. Jornada | 06.03.2022 | FK SKA Rostov | - | FK Druzhba | 1:0 |
Rusia