| 4. Jornada | 06.04.2021 | Atlético Porteño | - | Chacaritas FC | 1:3 |  |
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| 5. Jornada | 14.04.2021 | Liga de Portoviejo | - | Atlético Porteño | 1:2 | ||||
| 6. Jornada | 21.04.2021 | Atlético Porteño | - | Guayaquil SC | 3:4 | ||||
| 7. Jornada | 06.05.2021 | Cumbayá | - | Atlético Porteño | 2:1 | ||||
| 8. Jornada | 14.05.2021 | Atlético Porteño | - | Independiente Juniors | 1:4 |
Ecuador