| 1. Jornada | 07.08.2021 | SC Cham | - | FC Sion II | 2:1 |  |
|||
| 2. Jornada | 18.08.2021 | FC Sion II | - | FC Black Stars Basel | 0:0 | ||||
| 3. Jornada | 21.08.2021 | FC Bavois | - | FC Sion II | 3:1 | ||||
| 4. Jornada | 28.08.2021 | FC Sion II | - | FC Stade Nyonnais | 1:1 | ||||
| 5. Jornada | 04.09.2021 | AC Bellinzona | - | FC Sion II | 3:1 | |
|||
| 6. Jornada | 11.09.2021 | FC Sion II | - | BSC Young Boys II | 2:0 | ||||
| 8. Jornada | 25.09.2021 | FC Sion II | - | FC Biel/Bienne | 1:2 | ||||
| 7. Jornada | 29.09.2021 | FC Chiasso | - | FC Sion II | 1:2 | ||||
| 9. Jornada | 02.10.2021 | FC Basel 1893 II | - | FC Sion II | 6:2 | ||||
| 10. Jornada | 10.10.2021 | FC Rapperswil-Jona | - | FC Sion II | 2:0 | ||||
| 11. Jornada | 16.10.2021 | FC Sion II | - | Etoile Carouge FC | 0:0 | ||||
| 12. Jornada | 23.10.2021 | FC Zürich II | - | FC Sion II | 4:0 | ||||
| 13. Jornada | 30.10.2021 | FC Sion II | - | FC Breitenrain Bern | 3:7 | ||||
| 14. Jornada | 06.11.2021 | SC Brühl | - | FC Sion II | 0:1 | ||||
| 15. Jornada | 13.11.2021 | FC Sion II | - | SC YF/Juventus Zürich | 1:3 |
Suiza