| 1. Jornada | 24.07.2021 | FK Khimki | - | Zenit | 1:3 | ||||
| 2. Jornada | 01.08.2021 | FK Krasnodar | - | FK Khimki | 0:1 | ||||
| 3. Jornada | 08.08.2021 | FK Khimki | - | FK Rostov | 1:1 | ||||
| 4. Jornada | 16.08.2021 | FK Sochi | - | FK Khimki | 3:0 | ||||
| 7. Jornada | 11.09.2021 | Spartak Moskva | - | FK Khimki | 3:1 | ||||
| 8. Jornada | 18.09.2021 | FK Ufa | - | FK Khimki | 3:2 | ||||
| 9. Jornada | 25.09.2021 | FK Khimki | - | Lokomotiv Moskva | 0:0 | ||||
| 10. Jornada | 02.10.2021 | Arsenal Tula | - | FK Khimki | 0:0 |  |
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| 11. Jornada | 17.10.2021 | FK Khimki | - | Akhmat Grozny | 2:0 | ||||
| 12. Jornada | 22.10.2021 | Dinamo Moskva | - | FK Khimki | 4:1 | ||||
| 13. Jornada | 31.10.2021 | FK Khimki | - | FK Ural | 0:0 | ||||
| 14. Jornada | 06.11.2021 | Krylia Sovetov | - | FK Khimki | 3:0 | |
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| 15. Jornada | 21.11.2021 | CSKA Moscú | - | FK Khimki | 0:0 | ||||
| 16. Jornada | 27.11.2021 | FK Khimki | - | FK Krasnodar | 3:3 | |
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| 17. Jornada | 05.12.2021 | FK Khimki | - | Arsenal Tula | 1:2 | ||||
| 26. Jornada | 24.04.2022 | FK Khimki | - | Krylia Sovetov | 4:1 | ||||
| 27. Jornada | 01.05.2022 | FK Khimki | - | FK Ufa | 1:1 | |
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| 29. Jornada | 14.05.2022 | FK Rostov | - | FK Khimki | 2:1 | ||||
| 30. Jornada | 21.05.2022 | FK Khimki | - | Spartak Moskva | 2:1 |
Ucrania
Rusia