| 25. Jornada | 02.02.2005 | Birmingham City | - | Southampton | 2:1 |  |
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| 26. Jornada | 06.02.2005 | Southampton | - | Everton | 2:2 | ||||
| 27. Jornada | 22.02.2005 | West Bromwich Albion | - | Southampton | 0:0 | |
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| 28. Jornada | 26.02.2005 | Southampton | - | Arsenal | 1:1 | ||||
| 29. Jornada | 05.03.2005 | Southampton | - | Tottenham Hotspur | 1:0 | ||||
| 30. Jornada | 20.03.2005 | Middlesbrough | - | Southampton | 1:3 | ||||
| 31. Jornada | 02.04.2005 | Southampton | - | Chelsea | 1:3 | ||||
| 32. Jornada | 09.04.2005 | Blackburn Rovers | - | Southampton | 3:0 | ||||
| 33. Jornada | 16.04.2005 | Southampton | - | Aston Villa | 2:3 | ||||
| 35. Jornada | 24.04.2005 | Portsmouth FC | - | Southampton | 4:1 | ||||
| 36. Jornada | 30.04.2005 | Southampton | - | Norwich City | 4:3 | |
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| 37. Jornada | 07.05.2005 | Crystal Palace | - | Southampton | 2:2 | ||||
| 38. Jornada | 15.05.2005 | Southampton | - | Manchester United | 1:2 |
Francia