| 4. Jornada | 07.02.2016 | Club Rubio Ñu | - | General Díaz | 0:0 | ||||
| 5. Jornada | 12.02.2016 | General Díaz | - | Club Olimpia | 4:1 |  |
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| 6. Jornada | 20.02.2016 | Sol de América | - | General Díaz | 3:1 | ||||
| 7. Jornada | 27.02.2016 | General Díaz | - | Libertad | 1:0 | ||||
| 8. Jornada | 03.03.2016 | Club Nacional | - | General Díaz | 1:3 | ||||
| 9. Jornada | 06.03.2016 | General Díaz | - | Deportivo Capiatá | 2:2 | ||||
| 10. Jornada | 11.03.2016 | General Díaz | - | River Plate | 3:0 | |
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| 11. Jornada | 21.03.2016 | Cerro Porteño | - | General Díaz | 2:2 | ||||
| 3. Jornada | 26.03.2016 | General Díaz | - | Guaraní | 3:2 | ||||
| 14. Jornada | 11.04.2016 | Guaraní | - | General Díaz | 3:0 | |
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| 15. Jornada | 15.04.2016 | General Díaz | - | Club Rubio Ñu | 0:2 | ||||
| 16. Jornada | 21.04.2016 | Club Olimpia | - | General Díaz | 4:1 | ||||
| 17. Jornada | 27.04.2016 | General Díaz | - | Sol de América | 2:1 | ||||
| 18. Jornada | 02.05.2016 | Libertad | - | General Díaz | 2:1 | ||||
| 19. Jornada | 05.05.2016 | General Díaz | - | Club Nacional | 1:1 | ||||
| 20. Jornada | 10.05.2016 | Deportivo Capiatá | - | General Díaz | 2:1 | |
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| 21. Jornada | 14.05.2016 | River Plate | - | General Díaz | 1:1 | ||||
| 22. Jornada | 21.05.2016 | General Díaz | - | Cerro Porteño | 2:5 |
Paraguay