| 1. Jornada | 26.07.2020 | Deportivo Guadalajara | - | Club León | 0:0 | ||||
| 3. Jornada | 09.08.2020 | Cruz Azul | - | Club León | 2:0 | ||||
| 4. Jornada | 12.08.2020 | CF Pachuca | - | Club León | 0:1 | ||||
| 5. Jornada | 18.08.2020 | Club León | - | Club Tijuana | 2:1 | ||||
| 6. Jornada | 22.08.2020 | FC Juárez | - | Club León | 0:0 | ||||
| 7. Jornada | 01.09.2020 | Club León | - | Atlas Guadalajara | 2:1 | ||||
| 9. Jornada | 10.09.2020 | Club León | - | UANL Tigres | 1:1 | ||||
| 12. Jornada | 28.09.2020 | Atlético San Luis | - | Club León | 0:2 | ||||
| 14. Jornada | 20.10.2020 | Club León | - | CF América | 3:2 | ||||
| 15. Jornada | 24.10.2020 | Puebla FC | - | Club León | 1:2 | ||||
| 16. Jornada | 03.11.2020 | Club León | - | Santos Laguna | 2:1 | ||||
| 17. Jornada | 08.11.2020 | Deportivo Toluca | - | Club León | 2:2 |  |
México