| 1. Jornada | 11.01.2003 | Real San Luis | - | Gallos Blancos (old) | 1:1 | ||||
| 2. Jornada | 19.01.2003 | Puebla FC | - | Real San Luis | 0:1 | ||||
| 3. Jornada | 25.01.2003 | Real San Luis | - | CF América | 0:4 |  |
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| 4. Jornada | 01.02.2003 | Jaguares Chiapas | - | Real San Luis | 3:1 | |
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| 5. Jornada | 09.02.2003 | Real San Luis | - | Cruz Azul | 2:2 | ||||
| 6. Jornada | 16.02.2003 | UAG Tecos | - | Real San Luis | 1:2 | ||||
| 7. Jornada | 22.02.2003 | Real San Luis | - | UANL Tigres | 2:0 | ||||
| 8. Jornada | 02.03.2003 | CF Pachuca | - | Real San Luis | 2:2 | ||||
| 9. Jornada | 08.03.2003 | Real San Luis | - | Deportivo Guadalajara | 0:2 | |
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| 10. Jornada | 15.03.2003 | Atlético Cuernavaca | - | Real San Luis | 2:4 |  |
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| 11. Jornada | 23.03.2003 | Santos Laguna | - | Real San Luis | 2:0 | |
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| 12. Jornada | 29.03.2003 | Real San Luis | - | Club Necaxa | 1:0 | |
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| 14. Jornada | 12.04.2003 | Real San Luis | - | Monarcas Morelia | 2:4 | ||||
| 15. Jornada | 20.04.2003 | Pumas UNAM | - | Real San Luis | 2:2 | |
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| 16. Jornada | 26.04.2003 | Real San Luis | - | Veracruz (old) | 0:3 | ||||
| 18. Jornada | 10.05.2003 | Real San Luis | - | Deportivo Toluca | 2:3 |
Argentina