| 1. Jornada | 24.07.2021 | FC Luzern | - | BSC Young Boys | 3:4 |  |
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| 2. Jornada | 01.08.2021 | FC St. Gallen | - | FC Luzern | 2:2 | ||||
| 3. Jornada | 08.08.2021 | FC Luzern | - | FC Zürich | 1:3 | ||||
| 5. Jornada | 29.08.2021 | FC Luzern | - | FC Lausanne-Sport | 1:1 | |
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| 7. Jornada | 23.09.2021 | FC Sion | - | FC Luzern | 1:1 | |
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| 8. Jornada | 26.09.2021 | FC Luzern | - | FC Lugano | 2:3 | ||||
| 15. Jornada | 28.11.2021 | FC Luzern | - | Basilea | 1:3 |
Austria